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Autologous Conditioned plasma therapy for hair rejuvenation and hair growth, anti-ageing and treatment of Sports injuries
Autologous conditioned plasma (ACP), also known as PRP, refers to an Autologous plasma with a concentrated number of platelets and in which the erythrocytes and leukocytes have been separated out to the greatest extent. Platelets play a central role in wound healing and regeneration. They contain a variety of growth factors such as PDGF, TGF, VEGF, and EGF, which are released following activation by thrombin or collagen.
Platelet rich plasma has been clinically validated and established as a treatment concept in a wide variety of medical disciplines for a long time. PRP particularly appeals to patients looking for a natural treatment result without the use of foreign substances in addition to aesthetic medicine, dermatology and plastic surgery. PRP has also been used in Orthopedics and sports medicines for many years, primarily to treat muscle and tendon injuries and also in the treatment of Arthritis.
PRP is injected into the scalp for treatment option for hair loss. PRP stimulates the proliferation and differentiation of stem cells in hair follicles. The growth factor, VEGF triggers neoangiogenesis and simulates the blood supply to the hair follicles. In addition, the dormant hair follicles are stimulated by the growth factors released.
PRP is well tolerated and can produce a significant improvement in wrinkles without injection of a foreign substances, and with virtually no downtime. The procedure is especially beneficial for finer, superficial wrinkles. Studies also describe use of PRP in combination with fat grafts. PRP supports the vascularization and thus the preservation of the fat graft, among other things.
PRP when injected intradermally, stimulates the breakdown of sun damaged elements of the extracellular matrix and induces the synthesis of collagen. A significant improvements in skin elasticity has been reported in a number of studies as a direct result. It has also proved possible to demonstrate a considerably higher quantity of collagen bundles. The synthesis of hyaluronic acid stimulated by PRP has additionally been shown to produce a volume effect and enhance skin turgor. PRP is also ideal for combination with medical needling. Numerous studies have demonstrated how the combination of PRP and microneedling leads to better clinical results and higher patient satisfaction compared with microneedling alone.